Convergent TP53 loss and evolvability in cancer
Abstract Cancer cell populations evolve by a stepwise process involving natural selection of the fittest variants within a tissue ecosystem context and as modified by therapy. Genomic scrutiny of patient samples reveals an extraordinary diversity of mutational profiles both between patients with sim...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-09-01
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| Series: | BMC Ecology and Evolution |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12862-023-02146-6 |