Synthesis, in-vitro inhibition of cyclooxygenases and in silico studies of new isoxazole derivatives

Isoxazole belongs to the class of five-membered heterocyclic compounds. The process of developing new drugs has significantly gained attention due to inadequate pharmacokinetic and safety attributes of the available drugs. This study aimed to design a new diverse array of ten novel isoxazole derivat...

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Bibliographic Details
Main Authors: Waqas Alam, Haroon Khan, Muhammad Saeed Jan, Umer Rashid, Ali Abusharha, Maria Daglia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1222047/full