Synthesis, in-vitro inhibition of cyclooxygenases and in silico studies of new isoxazole derivatives

Isoxazole belongs to the class of five-membered heterocyclic compounds. The process of developing new drugs has significantly gained attention due to inadequate pharmacokinetic and safety attributes of the available drugs. This study aimed to design a new diverse array of ten novel isoxazole derivat...

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Hlavní autoři: Waqas Alam, Haroon Khan, Muhammad Saeed Jan, Umer Rashid, Ali Abusharha, Maria Daglia
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2023-09-01
Edice:Frontiers in Chemistry
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fchem.2023.1222047/full