Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1

Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1

Mutations in the human N-glycanase 1 (NGLY1) cause a rare, multisystem congenital disorder with global developmental delay. However, the mechanisms by which NGLY1 and its homologs regulate embryonic development are not known. Here we show that Drosophila Pngl encodes an N-glycanase and exhibits a hi...

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Bibliographic Details
Main Authors: Antonio Galeone, Seung Yeop Han, Chengcheng Huang, Akira Hosomi, Tadashi Suzuki, Hamed Jafar-Nejad
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
NGLY1
BMP signaling
Drosophila
midgut
Online Access:https://elifesciences.org/articles/27612

Internet

https://elifesciences.org/articles/27612

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