Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice

Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice

Abstract Background Recent findings show that extracellular vesicle constituents can exert short- and long-range biological effects on neighboring cells in the brain, opening an exciting avenue for investigation in the field of neurodegenerative diseases. Although it is well documented that extracel...

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Bibliographic Details
Main Authors: Melissa R. Pergande, Christina Kang, Diann George, Pearl A. Sutter, Stephen J. Crocker, Stephanie M. Cologna, Maria I. Givogri
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Lipids in Health and Disease
Subjects:
Lipidomic
Extracellular vesicles
Mass spectrometry
Metachromatic leukodystrophy
Online Access:https://doi.org/10.1186/s12944-022-01644-8

Internet

https://doi.org/10.1186/s12944-022-01644-8

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