SOX4 Mediates BRAF Inhibitor Resistance in Melanoma through Regulation of IGF-1R Signaling: In Vitro Study
Abstract. Objective:. SOX4, a transcription factor, has been found to contribute to tumorigenesis in several cancers. This study was performed to determine whether SOX4 mediates BRAF inhibitor resistance in melanoma. Methods:. Melanoma cell lines with acquired resistance to BRAF inhibitor (SK-MEL-5R...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Health
2020-09-01
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| Series: | International Journal of Dermatology and Venerology |
| Online Access: | http://journals.lww.com/10.1097/JD9.0000000000000107 |