Short-term zinc supplementation of zinc-deficient seniors counteracts CREMα - mediated IL-2 suppression

Short-term zinc supplementation of zinc-deficient seniors counteracts CREMα - mediated IL-2 suppression

Abstract Background Aging is accompanied by a dramatic decline in the interleukin (IL)-2 production capacity of human immune cells, thus making seniors more susceptible to a variety of age-related diseases. A common cause of impaired cytokine production in advanced age is a deficiency of the essenti...

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Bibliographic Details
Main Authors: Bastian Robinson Baarz, Thea Laurentius, Jana Wolf, Inga Wessels, Leo Cornelius Bollheimer, Lothar Rink
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Immunity & Ageing
Subjects:
Aging
Cytokines
Interleukin-2
Dietary supplements
Trace element
Zinc
Online Access:https://doi.org/10.1186/s12979-022-00295-8

Internet

https://doi.org/10.1186/s12979-022-00295-8

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