Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration

Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration

Oxidative stress develops as a response to injury and reflects a breach in the cell’s antioxidant capacity. Therefore, the fine-tuning of reactive oxygen species (ROS) generation is crucial for preserving cell’s homeostasis. Mitochondria are a major source and an immediate target of ROS. Under diffe...

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Bibliographic Details
Main Authors: Anna Picca, Riccardo Calvani, Hélio José Coelho-Junior, Francesco Landi, Roberto Bernabei, Emanuele Marzetti
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Antioxidants
Subjects:
Alzheimer’s disease
cytokines
DAMPs
Down syndrome
endo-lysosomal system
extracellular vesicles
Online Access:https://www.mdpi.com/2076-3921/9/8/647

Internet

https://www.mdpi.com/2076-3921/9/8/647

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