TBM Hunter: Identify and Score Canonical, Extended, and Unconventional Tankyrase-Binding Motifs in Any Protein

TBM Hunter: Identify and Score Canonical, Extended, and Unconventional Tankyrase-Binding Motifs in Any Protein

Tankyrases, a versatile protein group within the poly(ADP-ribose) polymerase family, are essential for post-translational poly(ADP-ribosyl)ation, influencing various cellular functions and contributing to diseases, particularly cancer. Consequently, tankyrases have become important targets for anti-...

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Bibliographic Details
Main Authors: Christopher M. Clements, Samantha X. Shellman, Melody H. Shellman, Yiqun G. Shellman
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
tankyrase (TNKS)
tankyrase 2 (TNKS2)
poly(ADP-ribosyl)ation (PARylation)
PARsylation
poly(ADP-ribose) polymerase (PARP)
tankyrase-binding motif (TBM)
Online Access:https://www.mdpi.com/1422-0067/24/23/16964

Internet

https://www.mdpi.com/1422-0067/24/23/16964

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