Comparative Characteristics of Inactivation Agents for HFRS Vaccine Development

The results of various methods of Puumala virus inactivation, including ultraviolet rays (UV), β -propiolactone (BPL) and formalin are presented. Immunogenicity of vaccine preparations obtained using these virus inactivation methods did not differ significantly in the experiments on BALB/c mice. Ess...

Full description

Bibliographic Details
Main Authors: C. C. Kurashova, A. A. Ishmukhametov, M. C. Egorova, M. V. Balovneva, T. K. Dzagurova, E. A. Tkachenko
Format: Article
Language:Russian
Published: Numikom LLC 2018-09-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
Online Access:https://www.epidemvac.ru/jour/article/view/556