OTULIN couples WNT signaling to resistance in triple-negative breast cancer

Oncogenic Wnt/β-catenin activation promotes cancer development and drug resistance to cancer treatments. We recently revealed an underlying mechanism linking linear ubiquitination with Wnt/β-catenin activation upon genotoxic treatments. We showed that ABL1 (ABL proto-oncogene 1)-dependent phosphoryl...

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Bibliographic Details
Main Authors: Wei Wang, Zhao-Hui Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2020.1825904