Combining IP3 affinity chromatography and bioinformatics reveals a novel protein-IP3 binding site on Plasmodium falciparum MDR1 transporter

Intracellular Ca2+ mobilization induced by second messenger IP3 controls many cellular events in most of the eukaryotic groups. Despite the increasing evidence of IP3-induced Ca2+ in apicomplexan parasites like Plasmodium, responsible for malaria infection, no protein with potential function as an I...

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Bibliographic Details
Main Authors: Eduardo Alves, Helder Nakaya, Euzébio Guimarães, Célia R.S. Garcia
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Microbial Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517422000761