MYCN and the Epigenome

MYCN and the Epigenome

It is well known that Neuroblastoma (NB) patients whose tumors have an undifferentiated histology and a transcriptome enriched in cell cycle genes have a worse prognosis. This contrasts with the good prognoses of patients whose tumors have histologic evidence of differentiation and a transcriptome e...

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Bibliographic Details
Main Authors: Stanley eHe, Zhihui eLiu, Doo-Yi eOh, Carol J Thiele
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Oncology
Subjects:
RNA Polymerase II
Transcriptional Activation
epigenetics
epigenome
MYCN
HDAC
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00001/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00001/full

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