Necroptosis occurs in osteoblasts during tumor necrosis factor-α stimulation and caspase-8 inhibition

Necroptosis occurs in osteoblasts during tumor necrosis factor-α stimulation and caspase-8 inhibition

Necroptosis is a regulated cell death mechanism. However, it is unknown whether necroptosis is involved in the death of tumor necrosis factor-α (TNF-α)-treated osteoblasts. Therefore, we conducted the study with TNF-α, Nec-1 (a specific inhibitor of necroptosis), and Z-IETD-FMK (a specific inhibitor...

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Bibliographic Details
Main Authors: Guan Shi, Pu Jia, Hao Chen, Li Bao, Fei Feng, Hai Tang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Necroptosis
Mouse osteoblast
Z-IETD-FMK
Necrostatin-1
TNF-α
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000100603&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000100603&lng=en&tlng=en

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