Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors

The strength of goal-oriented behaviors is regulated by midbrain dopamine neurons. Dysfunctions of dopaminergic circuits are observed in drug addiction and obsessive-compulsive disorder. Compulsive behavior is a feature that both disorders share, which is associated to a heightened dopamine neurotra...

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Bibliographic Details
Main Authors: Angélica del Pilar Escobar, José Patricio Casanova, María Estela Andrés, José Antonio Fuentealba
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00057/full