Differential Effects of Aripiprazole on Electroencephalography-Recorded Gamma-Band Auditory Steady-State Response, Spontaneous Gamma Oscillations and Behavior in a Schizophrenia Rat Model

Differential Effects of Aripiprazole on Electroencephalography-Recorded Gamma-Band Auditory Steady-State Response, Spontaneous Gamma Oscillations and Behavior in a Schizophrenia Rat Model

The available antipsychotics for schizophrenia (SZ) only reduce positive symptoms and do not significantly modify SZ neurobiology. This has raised the question of the robustness and translational value of methods employed during drug development. Electroencephalography (EEG)-based measures like evok...

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Bibliographic Details
Main Authors: Florian W. Adraoui, Kenza Hettak, Geoffrey Viardot, Magali Alix, Sabrina Guiffard, Benoît Meot, Philippe L’Hostis, Anne Maurin, Eric Delpy, Christophe Drieu La Rochelle, Kevin Carvalho
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
schizophrenia
aripiprazole
gamma-band ASSR
spontaneous gamma oscillations
drug development
NMDAr hypofunction
Online Access:https://www.mdpi.com/1422-0067/25/2/1035

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https://www.mdpi.com/1422-0067/25/2/1035

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