Chronic LCMV Infection Is Fortified with Versatile Tactics to Suppress Host T Cell Immunity and Establish Viral Persistence

Ever since the immune regulatory strains of lymphocytic choriomeningitis virus (LCMV), such as Clone 13, were isolated, LCMV infection of mice has served as a valuable model for the mechanistic study of viral immune suppression and virus persistence. The exhaustion of virus-specific T cells was demo...

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Bibliographic Details
Main Authors: Caleb J. Studstill, Bumsuk Hahm
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/10/1951