The Distribution and Role of the CFTR Protein in the Intracellular Compartments

Cystic fibrosis is a hereditary disease that mainly affects secretory organs in humans. It is caused by mutations in the gene encoding CFTR with the most common phenylalanine deletion at position 508. CFTR is an anion channel mainly conducting Cl<sup>−</sup> across the apical membranes o...

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Bibliographic Details
Main Authors: Agnieszka Lukasiak, Miroslaw Zajac
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/11/11/804