Raja 42, a novel gamma lactam compound, is effective against Clostridioides difficile.

Clostridioides difficile infection (CDI) is the primary cause of hospital-acquired diarrhea, and responsible for over 500,000 enteric infections a year in the United States alone. Although most patients with CDI are successfully treated with metronidazole or vancomycin, the high rate of recurrence i...

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Bibliographic Details
Main Authors: Alexis Fong, Megan Ross, Justin Boudreau, Reza Nokhbeh, Kim Tilbe, Hoyun Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0257143