A novel small molecule inhibitor of human Drp1

A novel small molecule inhibitor of human Drp1

Abstract Mitochondrial dynamin-related protein 1 (Drp1) is a large GTPase regulator of mitochondrial dynamics and is known to play an important role in numerous pathophysiological processes. Despite being the most widely used Drp1 inhibitor, the specificity of Mdivi-1 towards human Drp1 has not been...

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Bibliographic Details
Main Authors: Ayeshah A. Rosdah, Belinda M. Abbott, Christopher G. Langendorf, Yali Deng, Jia Q. Truong, Helen M. M. Waddell, Naomi X. Y. Ling, William J. Smiles, Lea M. D. Delbridge, Guei-Sheung Liu, Jonathan S. Oakhill, Shiang Y. Lim, Jessica K. Holien
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25464-z

Internet

https://doi.org/10.1038/s41598-022-25464-z

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