Cellular hierarchy framework based on single-cell/multi-patient sample sequencing reveals metabolic biomarker PYGL as a therapeutic target for HNSCC

Cellular hierarchy framework based on single-cell/multi-patient sample sequencing reveals metabolic biomarker PYGL as a therapeutic target for HNSCC

Abstract Background A growing body of research has revealed the connection of metabolism reprogramming and tumor progression, yet how metabolism reprogramming affects inter-patient heterogeneity and prognosis in head and neck squamous cell carcinoma (HNSCC) still requires further explorations. Metho...

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Bibliographic Details
Main Authors: Jiezhong Guan, Xi Xu, Guo Qiu, Chong He, Xiaoyue Lu, Kang Wang, Xinyu Liu, Yuanyuan Li, Zihang Ling, Xuan Tang, Yujie Liang, Xiaoan Tao, Bin Cheng, Bo Yang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
HNSCC
Cellular hierarchy framework
Single-cell sequencing
Cell metabolism reprogramming
PYGL
Online Access:https://doi.org/10.1186/s13046-023-02734-w

Internet

https://doi.org/10.1186/s13046-023-02734-w

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