Combination of Six Individual Derivatives of the Pom-1 Antibiofilm Peptide Doubles Their Efficacy against Invasive and Multi-Resistant Clinical Isolates of the Pathogenic Yeast <i>Candida</i> <i>albicans</i>

Combination of Six Individual Derivatives of the Pom-1 Antibiofilm Peptide Doubles Their Efficacy against Invasive and Multi-Resistant Clinical Isolates of the Pathogenic Yeast <i>Candida</i> <i>albicans</i>

In previous studies, derivatives of the peptide Pom-1, which was originally extracted from the freshwater mollusk <i>Pomacea poeyana,</i> showed an exceptional ability to specifically inhibit biofilm formation of the laboratory strain ATCC 90028 as a model strain of the pathogenic yeast...

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Bibliographic Details
Main Authors: Michelle Häring, Valerie Amann, Ann-Kathrin Kissmann, Tilmann Herberger, Christopher Synatschke, Nicole Kirsch-Pietz, Julio A. Perez-Erviti, Anselmo J. Otero-Gonzalez, Fidel Morales-Vicente, Jakob Andersson, Tanja Weil, Steffen Stenger, Armando Rodríguez, Ludger Ständker, Frank Rosenau
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
antimicrobial peptides
invasive clinical isolates
combination therapy
Online Access:https://www.mdpi.com/1999-4923/14/7/1332

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https://www.mdpi.com/1999-4923/14/7/1332

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