Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease

Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease

The current understanding of molecular mechanisms driving diabetic kidney disease (DKD) is limited, partly due to the complex structure of the kidney. To identify genes and signalling pathways involved in the progression of DKD, we compared kidney cortical versus glomerular transcriptome profiles in...

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Bibliographic Details
Main Authors: Frederikke E. Sembach, Helene M. Ægidius, Lisbeth N. Fink, Thomas Secher, Annemarie Aarup, Jacob Jelsing, Niels Vrang, Bo Feldt-Rasmussen, Kristoffer T. G. Rigbolt, Jens C. Nielsen, Mette V. Østergaard
Format: Article
Language:English
Published: The Company of Biologists 2021-10-01
Series:Disease Models & Mechanisms
Subjects:
diabetic kidney disease
mouse model
laser-capture microdissection
single-nucleus
glomerulus
rnaseq
Online Access:http://dmm.biologists.org/content/14/10/dmm049086

Internet

http://dmm.biologists.org/content/14/10/dmm049086

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