Causal relationship between Interleukin-27 expression levels and osteoporosis: a bidirectional mendelian randomization study

Causal relationship between Interleukin-27 expression levels and osteoporosis: a bidirectional mendelian randomization study

Abstract Background This study aimed to evaluate the causal relationship between Interleukin-27 (IL-27) and osteoporosis by bidirectional Mendelian randomization (MR) analysis. Methods Firstly, the genome-wide association study summary data of osteoporosis (finn-b-M13_OSTEOPOROSIS) and IL-27 levels...

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Bibliographic Details
Main Authors: Yun Xue, You Zhou, Chunyan Li, Jingshuang Zhang, Fei Liu, Rui Shi
Format: Article
Language:English
Published: BMC 2024-08-01
Series:BMC Musculoskeletal Disorders
Subjects:
Osteoporosis
Interleukin-27
Mendelian randomization
Causality
Enrichment analysis
Online Access:https://doi.org/10.1186/s12891-024-07765-8

Internet

https://doi.org/10.1186/s12891-024-07765-8

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