The metastatic capacity of high-grade serous ovarian cancer cells changes along disease progression: inhibition by mifepristone
Abstract Background Simplistic two-dimensional (2D) in vitro assays have long been the standard for studying the metastatic abilities of cancer cells. However, tri-dimensional (3D) organotypic models provide a more complex environment, closer to that seen in patients, and thereby provide a more accu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-022-02822-5 |