The metastatic capacity of high-grade serous ovarian cancer cells changes along disease progression: inhibition by mifepristone

Abstract Background Simplistic two-dimensional (2D) in vitro assays have long been the standard for studying the metastatic abilities of cancer cells. However, tri-dimensional (3D) organotypic models provide a more complex environment, closer to that seen in patients, and thereby provide a more accu...

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Bibliographic Details
Main Authors: Sabrina J. Ritch, Abu Shadat M. Noman, Alicia A. Goyeneche, Carlos M. Telleria
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02822-5