Impact of Medical Castration on Malignant Arrhythmias in Patients With Prostate Cancer

Impact of Medical Castration on Malignant Arrhythmias in Patients With Prostate Cancer

Background Medical castration, gonadotropin‐releasing hormone agonists, and antiandrogens have been widely applied as a treatment for prostate cancer. Sex steroid hormones influence cardiac ion channels. However, few studies have examined the proarrhythmic properties of medical castration. Methods a...

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Bibliographic Details
Main Authors: Kanae Hasegawa, Hideaki Ito, Kenichi Kaseno, Shinsuke Miyazaki, Yuichiro Shiomi, Naoto Tama, Hiroyuki Ikeda, Kentaro Ishida, Hiroyasu Uzui, Seiko Ohno, Minoru Horie, Osamu Yokoyama, Hiroshi Tada
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
medical castration
prostate cancer
QT prolongation
torsade de pointes
ventricular fibrillation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.017267

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.017267

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