Biochanin A abrogates osteoclastogenesis in type 2 diabetic osteoporosis via regulating ROS/MAPK signaling pathway based on integrating molecular docking and experimental validation

Biochanin A abrogates osteoclastogenesis in type 2 diabetic osteoporosis via regulating ROS/MAPK signaling pathway based on integrating molecular docking and experimental validation

Abstract Background There are accumulating type 2 diabetes patients who have osteoporosis simultaneously. More effective therapeutic strategies should be discovered. Biochanin A (BCA) has been indicated that can play a role in improving metabolic disorders of type 2 diabetes and preventing osteoporo...

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Bibliographic Details
Main Authors: Qi He, Junzheng Yang, Weijian Chen, Zhaofeng Pan, Baihao Chen, Jiaxu Zeng, Nenling Zhang, Yuewei Lin, Chuyi Chen, Jiacong Xiao, Miao Li, Shaocong Li, Haibin Wang, Peng Chen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Biochanin A
Type 2 diabetic osteoporosis
Osteoclasts
Oxidative stress
MAPK signaling pathway
Online Access:https://doi.org/10.1186/s12906-023-04332-x

Internet

https://doi.org/10.1186/s12906-023-04332-x

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