Effects of long-acting muscarinic antagonists on promoting ciliary function in airway epithelium

Effects of long-acting muscarinic antagonists on promoting ciliary function in airway epithelium

Abstract Background Mucociliary clearance (MCC) is an essential defense mechanism in airway epithelia for removing pathogens from the respiratory tract. Impaired ciliary functions and MCC have been demonstrated in asthma and chronic obstructive pulmonary disease (COPD). Long-acting muscarinic antago...

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Main Authors: Mineo Katsumata, Tomoyuki Fujisawa, Yosuke Kamiya, Yuko Tanaka, Chiaki Kamiya, Yusuke Inoue, Hironao Hozumi, Masato Karayama, Yuzo Suzuki, Kazuki Furuhashi, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Masato Maekawa, Mitsutoshi Setou, Hiroshi Watanabe, Koji Ikegami, Takafumi Suda
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Pulmonary Medicine
Subjects:
Asthma
Airway epithelium
Ciliary beat frequency
COPD
Long-acting muscarinic antagonists
Mucociliary clearance
Online Access:https://doi.org/10.1186/s12890-022-01983-3

Internet

https://doi.org/10.1186/s12890-022-01983-3

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