OncoRTT: Predicting novel oncology-related therapeutic targets using BERT embeddings and omics features

Late-stage drug development failures are usually a consequence of ineffective targets. Thus, proper target identification is needed, which may be possible using computational approaches. The reason being, effective targets have disease-relevant biological functions, and omics data unveil the protein...

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Bibliographic Details
Main Authors: Maha A. Thafar, Somayah Albaradei, Mahmut Uludag, Mona Alshahrani, Takashi Gojobori, Magbubah Essack, Xin Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1139626/full