Drug Repositioning in Glioblastoma: A Pathway Perspective

Drug Repositioning in Glioblastoma: A Pathway Perspective

Glioblastoma multiforme (GBM) is the most malignant primary adult brain tumor. The current standard of care is surgical resection, radiation, and chemotherapy treatment, which extends life in most cases. Unfortunately, tumor recurrence is nearly universal and patients with recurrent glioblastoma typ...

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Bibliographic Details
Main Authors: Sze Kiat Tan, Anna Jermakowicz, Adnan K. Mookhtiar, Charles B. Nemeroff, Stephan C. Schürer, Nagi G. Ayad
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Pharmacology
Subjects:
glioblastoma
drug repurposing
blood-brain barrier
Library of Integrated Network Based Cell Signatures
LINCS
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00218/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00218/full

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