Binding of Hepatitis B Virus Pre-S1 Domain-Derived Synthetic Myristoylated Peptide to Scavenger Receptor Class B Type 1 with Differential Properties from Sodium Taurocholate Cotransporting Polypeptide

Binding of Hepatitis B Virus Pre-S1 Domain-Derived Synthetic Myristoylated Peptide to Scavenger Receptor Class B Type 1 with Differential Properties from Sodium Taurocholate Cotransporting Polypeptide

(1) Background: The myristoylated pre-S1 peptide (Myr47) synthesized to mimic pre-S1 domain (2-48) in large (L) surface protein of hepatitis B virus (HBV) prevents HBV infection to hepatocytes by binding to sodium taurocholate cotransporting polypeptide (NTCP). We previously demonstrated that yeast-...

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Bibliographic Details
Main Authors: Shuji Hinuma, Shun’ichi Kuroda
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Viruses
Subjects:
hepatitis B virus (HBV)
myristoylated pre-S1 peptide (Myr47)
scavenger receptor class B type 1 (SR-B1)
sodium taurocholate cotransporting polypeptide (NTCP)
HEK293T cells
yeast-derived nanoparticles containing L protein (bio-nanocapsules: BNCs)
Online Access:https://www.mdpi.com/1999-4915/14/1/105

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https://www.mdpi.com/1999-4915/14/1/105

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