Characterization of a heme-regulated non-coding RNA encoded by the prrF locus of Pseudomonas aeruginosa.

Pseudomonas aeruginosa, an opportunistic pathogen, requires iron for virulence and can obtain this nutrient via the acquisition of heme, an abundant source of iron in the human body. A surplus of either iron or heme can lead to oxidative stress; thus, the Fur (ferric uptake regulator) protein blocks...

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Bibliographic Details
Main Authors: Amanda G Oglesby-Sherrouse, Michael L Vasil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2851614?pdf=render