Bizonal cardiac engineered tissues with differential maturation features in a mid-throughput multimodal bioreactor

Summary: Functional three-dimensional (3D) engineered cardiac tissue (ECT) models are essential for effective drug screening and biological studies. Application of physiological cues mimicking those typical of the native myocardium is known to promote the cardiac maturation and functionality in vitr...

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Bibliographic Details
Main Authors: Alessia Pisanu, Gregory Reid, Deborah Fusco, Antonio Sileo, Diana Robles Diaz, Hadi Tarhini, Giovanni Putame, Diana Massai, Giuseppe Isu, Anna Marsano
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222005673