Development, In-Vitro Characterization and Preclinical Evaluation of Esomeprazole-Encapsulated Proniosomal Formulation for the Enhancement of Anti-Ulcer Activity

Development, In-Vitro Characterization and Preclinical Evaluation of Esomeprazole-Encapsulated Proniosomal Formulation for the Enhancement of Anti-Ulcer Activity

<b>Objective:</b> The present study aimed to develop and optimize esomeprazole loaded proniosomes (EZL-PNs) to improve bioavailability and therapeutic efficacy. <b>Method:</b> EZL-PNs formulation was developed by slurry method and optimized by 33 box-Bhekhen statistical desig...

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Bibliographic Details
Main Authors: Dibyalochan Mohanty, Ameeduzzafar Zafar, Mohammed Jafar, Atul Kumar Upadhyay, Mohammad Akiful Haque, Jeetendra Kumar Gupta, Vasudha Bakshi, Mohammed M. Ghoneim, Sultan Alshehri, Mohammed Asadullah Jahangir, Mohammed Javed Ansari
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
esomeprazole
proniosomes
Box–Behnken statistical design
pharmacokinetic
Anti-ulcer activity
Online Access:https://www.mdpi.com/1420-3049/27/9/2748

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https://www.mdpi.com/1420-3049/27/9/2748

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