Tk-deleted pseudorabies virus retains high pathogenicity in rats
The pseudorabies virus (PRV) gene encoding thymidine kinase (tk) is an important virulence-associated factor. Attenuation of PRV in susceptible animals is a frequent result of tk deletion. The aim of the study was to assess the pathogenicity of tk-deleted PRV in rats.
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2021-10-01
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Series: | Journal of Veterinary Research |
Subjects: | |
Online Access: | https://doi.org/10.2478/jvetres-2021-0056 |