Tk-deleted pseudorabies virus retains high pathogenicity in rats
The pseudorabies virus (PRV) gene encoding thymidine kinase (tk) is an important virulence-associated factor. Attenuation of PRV in susceptible animals is a frequent result of tk deletion. The aim of the study was to assess the pathogenicity of tk-deleted PRV in rats.
Bibliographic Details
| Main Authors: |
Zhang Lirong,
Ruan Keyue,
Sang Guoju,
Xu Zhaoyang,
Tong Wu,
Yu Hai,
Shan Tongling,
Gao Fei,
Li Liwei,
Kong Ning,
Tong Guangzhi,
Zheng Hao |
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| Format: | Article
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| Language: | English |
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| Published: |
Sciendo
2021-10-01
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| Series: | Journal of Veterinary Research
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| Subjects: | |
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| Online Access: | https://doi.org/10.2478/jvetres-2021-0056
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