MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
All five muscarinic receptors have important physiological roles. The endothelial M2 and M3 subtypes regulate arterial tone through direct coupling to Gq or Gi/o proteins. Yet, we lack selective pharmacological drugs to assess the respective contribution of muscarinic receptors to a given function....
Main Authors: | Justyna Ciolek, Claude Zoukimian, Justine Dhot, Mélanie Burban, Mathilde Triquigneaux, Benjamin Lauzier, Christelle Guimbert, Didier Boturyn, Marine Ferron, Lidia Ciccone, Livia Tepshi, Enrico Stura, Pierre Legrand, Philippe Robin, Gilles Mourier, Béatrice Schaack, Imen Fellah, Guillaume Blanchet, Chantal Gauthier-Erfanian, Rémy Beroud, Denis Servent, Michel De Waard, Nicolas Gilles |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2022-06-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332222004838 |
Similar Items
-
Peptide characterization and application protocols /
by: Fields, Gregg B.
Published: (2007) -
Chemical Synthesis of a Functional Fluorescent-Tagged α-Bungarotoxin
by: Oliver Brun, et al.
Published: (2022-01-01) -
Strategies for Improving Peptide Stability and Delivery
by: Othman Al Musaimi, et al.
Published: (2022-10-01) -
Confocal Laser Scanning Microscopy and Model Membranes to Study Translocation Mechanisms of Membrane Active Peptides
by: Corina Ciobanasu
Published: (2022-08-01) -
Antimicrobial peptides : in human health and disease /
by: Gallo, Richard L.
Published: (2005)