Upregulation of galectin-3 in influenza A virus infection promotes viral RNA synthesis through its association with viral PA protein

Upregulation of galectin-3 in influenza A virus infection promotes viral RNA synthesis through its association with viral PA protein

Abstract Background Influenza is one of the most important viral infections globally. Viral RNA-dependent RNA polymerase (RdRp) consists of the PA, PB1, and PB2 subunits, and the amino acid residues of each subunit are highly conserved among influenza A virus (IAV) strains. Due to the high mutation...

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Bibliographic Details
Main Authors: Mei-Lin Yang, Yi-Cheng Chen, Chung-Teng Wang, Hao-Earn Chong, Nai-Hui Chung, Chia-Hsing Leu, Fu-Tong Liu, Michael M. C. Lai, Pin Ling, Chao-Liang Wu, Ai-Li Shiau
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Biomedical Science
Subjects:
Galectin-3
Influenza virus
vRNP import
RNA-dependent RNA polymerase
RNA synthesis
Viral PA
Online Access:https://doi.org/10.1186/s12929-023-00901-x

Internet

https://doi.org/10.1186/s12929-023-00901-x

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