Tangshenping granule inhibits pyroptosis in a rat model of streptozotocin-induced diabetic nephropathy via the NLRP3/caspase-1/GSDMD pathway

Objective: To explore the inhibitory effect of Tangshenping (TSP) on pyroptosis in a streptozotocin-induced diabetic nephropathy (DN) rat model. Methods: DN was established in Sprague–Dawley rats. Rats were randomly divided into DN (model group), irbesartan, and TSP low-, medium-, and high-dose grou...

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Bibliographic Details
Main Authors: Kun Gao, Pengfei Zheng, Tao Yang, Xinxue Zhang, Zongjiang Zhao
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754821000685