Facile Synthesis of Optically Active Imidazole Derivatives

Five optically active imidazole derivatives have been synthesized via a facile 4-step reaction sequence starting from commercially available and inexpensive N-Cbz amino acids. While microwave assisted condensation was unsuccessful, the condensation of the corresponding α-bromoketones with formami...

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Bibliographic Details
Main Authors: Filip Bures, Miroslav Ludwig, Jiri Kulhanek, Ales Marek
Format: Article
Language:English
Published: MDPI AG 2007-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/12/5/1183/