Synthesis of 1-(4-phenoxyphenyl)-3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]propan-1-ones as safer anti-inflammatory and analgesic agents

Synthesis of 1-(4-phenoxyphenyl)-3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]propan-1-ones as safer anti-inflammatory and analgesic agents

A novel series of 1-(4-phenoxyphenyl)-3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]propan-1-one was synthesized by reaction of 3-(4-phenoxybenzoyl)propionic acid with several aryl acid hydrazides in phosphorus oxychloride. The structures of the compounds were supported by IR, 1H- and 13C-NMR, MS dat...

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Bibliographic Details
Main Authors: ASIF HUSAIN, F. J. AHMAD, MOHD AJMAL, PRIYANKA AHUJA
Format: Article
Language:English
Published: Serbian Chemical Society 2008-08-01
Series:Journal of the Serbian Chemical Society
Subjects:
1
3
4-oxadiazole
anti-inflammatory
analgesic
ulcerogenic
lipid peroxidation
Online Access:http://www.shd.org.yu/JSCS/Vol73/No8-9/JSCS-3761.pdf

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http://www.shd.org.yu/JSCS/Vol73/No8-9/JSCS-3761.pdf

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