Comparative Analysis of Cell–Cell Contact Abundance in Ovarian Carcinoma Cells Cultured in Two- and Three-Dimensional In Vitro Models

Comparative Analysis of Cell–Cell Contact Abundance in Ovarian Carcinoma Cells Cultured in Two- and Three-Dimensional In Vitro Models

Tumor resistance to therapy is associated with the 3D organization and peculiarities of the tumor microenvironment, of which intercellular adhesion is a key participant. In this work, the abundance of contact proteins was compared in SKOV-3 and SKOV-3.ip human ovarian adenocarcinoma cell lines, cult...

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Bibliographic Details
Main Authors: Olga M. Kutova, Ludmila M. Sencha, Anton D. Pospelov, Olga E. Dobrynina, Anna A. Brilkina, Elena I. Cherkasova, Irina V. Balalaeva
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biology
Subjects:
cell–cell contacts
cancer resistance
tumor spheroids
collagen hydrogel
adherens junctions
desmosomes
Online Access:https://www.mdpi.com/2079-7737/9/12/446

Internet

https://www.mdpi.com/2079-7737/9/12/446

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