Towards the detection of copy number variation from single sperm sequencing in cattle

Towards the detection of copy number variation from single sperm sequencing in cattle

Abstract Background Copy number variation (CNV) has been routinely studied using bulk-cell sequencing. However, CNV is not well studied on the single-cell level except for humans and a few model organisms. Results We sequenced 143 single sperms of two Holstein bulls, from which we predicted CNV even...

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Bibliographic Details
Main Authors: Liu Yang, Yahui Gao, Adam Oswalt, Lingzhao Fang, Clarissa Boschiero, Mahesh Neupane, Charles G. Sattler, Cong-jun Li, Eyal Seroussi, Lingyang Xu, Lv Yang, Li Li, Hongping Zhang, Benjamin D. Rosen, Curtis P. Van Tassell, Yang Zhou, Li Ma, George E. Liu
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Genomics
Subjects:
Cattle
Single sperm sequencing
Copy number variation
Online Access:https://doi.org/10.1186/s12864-022-08441-8

Internet

https://doi.org/10.1186/s12864-022-08441-8

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