pRb-Independent Growth Arrest and Transcriptional Regulation of E2F Target Genes

The retinoblastoma tumor suppressor (pRb) has traditionally been studied as a negative regulator of cell cycle progression through its interactions with the E2F family of transcription factors. Utilizing prostate epithelial cell lines established from Rb+/+ and Rb-/- prostate tissues, we previously...

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Bibliographic Details
Main Authors: Michael T. McCabe, Odinaka J. Azih, Mark L. Day
Format: Article
Language:English
Published: Elsevier 2005-02-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800156