pRb-Independent Growth Arrest and Transcriptional Regulation of E2F Target Genes
The retinoblastoma tumor suppressor (pRb) has traditionally been studied as a negative regulator of cell cycle progression through its interactions with the E2F family of transcription factors. Utilizing prostate epithelial cell lines established from Rb+/+ and Rb-/- prostate tissues, we previously...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-02-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558605800156 |