A combined opposite targeting of p110δ PI3K and RhoA abrogates skin cancer

A combined opposite targeting of p110δ PI3K and RhoA abrogates skin cancer

Abstract Malignant melanoma is the most aggressive and deadly skin cancer with an increasing incidence worldwide whereas SCC is the second most common non-melanoma human skin cancer with limited treatment options. Here we show that the development and metastasis of melanoma and SCC cancers can be bl...

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Bibliographic Details
Main Authors: Niki Tzenaki, Lydia Xenou, Evangelia Goulielmaki, Anna Tsapara, Irene Voudouri, Angelika Antoniou, George Valianatos, Maria Tzardi, Eelco De Bree, Aikaterini Berdiaki, Antonios Makrigiannakis, Evangelia A. Papakonstanti
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05639-8

Internet

https://doi.org/10.1038/s42003-023-05639-8

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