Down-regulation of DNA key protein-FEN1 inhibits OSCC growth by affecting immunosuppressive phenotypes via IFN-γ/JAK/STAT-1
Abstract Oral squamous cell carcinoma (OSCC) escape from the immune system is mediated through several immunosuppressive phenotypes that are critical to the initiation and progression of tumors. As a hallmark of cancer, DNA damage repair is closely related to changes in the immunophenotypes of tumor...
Main Authors: | Shimeng Wang, Xiangjian Wang, Jun Sun, Jin Yang, Deyang Wu, Fanglong Wu, Hongmei Zhou |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-04-01
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Series: | International Journal of Oral Science |
Online Access: | https://doi.org/10.1038/s41368-023-00221-8 |
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