Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue

Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue

Objective: Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the function of Beclin1 in adipocyte metabolism has not been investigated. In the present study, we aimed to study the role of Beclin1 in li...

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Bibliographic Details
Main Authors: Yeonho Son, Yoon Keun Cho, Abhirup Saha, Hyun-Jung Kwon, Ji-Hyun Park, Minsu Kim, Young-Suk Jung, Sang-Nam Kim, Cheoljun Choi, Je-Kyung Seong, Rayanne B. Burl, James G. Granneman, Yun-Hee Lee
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Metabolism
Subjects:
Beclin1
Lipophagy
Mitophagy
Lipolysis
Brown adipose tissue
White adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S221287782030079X

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http://www.sciencedirect.com/science/article/pii/S221287782030079X

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