Potential Osteoinductive Effects of Hydroxyapatite Nanoparticles on Mesenchymal Stem Cells by Endothelial Cell Interaction

Potential Osteoinductive Effects of Hydroxyapatite Nanoparticles on Mesenchymal Stem Cells by Endothelial Cell Interaction

Abstract Nano-hydroxyapatite (nano-HA) has attracted substantial attention in the field of regenerative medicine. Endothelial cell (EC)-mesenchymal stem cell (MSC) interactions are necessary for bone reconstruction, but the manner in which nano-HA interacts in this process remains unknown. Herein, w...

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Bibliographic Details
Main Authors: Zhongyi Wang, Tianlei Han, Haoqi Zhu, Jinxin Tang, Yanyang Guo, Yabing Jin, Yu Wang, Guilan Chen, Ning Gu, Chen Wang
Format: Article
Language:English
Published: SpringerOpen 2021-04-01
Series:Nanoscale Research Letters
Subjects:
Hydroxyapatite nanoparticles
HWJ-MSC
HUVEC
HIF-1α
ERK1/2 pathway
Two-stage cell-lineage model
Online Access:https://doi.org/10.1186/s11671-021-03522-1

Internet

https://doi.org/10.1186/s11671-021-03522-1

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