Toxic Shock Syndrome Toxin 1 Evaluation and Antibiotic Impact in a Transgenic Model of Staphylococcal Soft Tissue Infection

Toxic Shock Syndrome Toxin 1 Evaluation and Antibiotic Impact in a Transgenic Model of Staphylococcal Soft Tissue Infection

ABSTRACT Nonmenstrual toxic shock syndrome (nmTSS), linked to TSST-1-producing CC30 Staphylococcus aureus, is the leading manifestation of toxic shock syndrome (TSS). Due to case rarity and a lack of tractable animal models, TSS pathogenesis is poorly understood. We developed an S. aureus abscess mo...

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Bibliographic Details
Main Authors: Hema Sharma, Claire E. Turner, Matthew K. Siggins, Mona El-Bahrawy, Bruno Pichon, Angela Kearns, Shiranee Sriskandan
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mSphere
Subjects:
antibiotics
dissemination
HLA-DQ8
nonmenstrual toxic shock syndrome
Staphylococcus aureus
TSST-1
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00665-19

Internet

https://journals.asm.org/doi/10.1128/mSphere.00665-19

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