Catalyzed and non-catalyzed synthesis of bioactive monastrol

Catalyzed and non-catalyzed synthesis of bioactive monastrol

The bioactive 3,4-dihydropyrimidin-2(1H)-thione derivative known as Monastrol was synthesized under catalyzed and non-catalyzed conditions through the Biginelli multicomponent reaction under solvent-free conditions. The use of two Lewis acids (FeCl3 and CuCl2) and two Brønsted acids (HCl and CF3COOH...

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Bibliographic Details
Main Authors: Haline G. O. Alvim, Jose R. Correa, Taynara R. Machado, Wender A. Silva, Brenno A. D. Neto
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2014-01-01
Series:Química Nova
Subjects:
Monastrol
Biginelli
multicomponent reaction
catalysis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014001000022&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014001000022&lng=en&tlng=en

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